EDITORIALThe article on alternative medicine in last month's issue generated a fair amount of feedback. The most interesting comments came from Dr. Michael Greenwood, a Canadian physician who is a pioneer in the treatment of chronic pain. While I do not necessarily agree with all of his comments, I wholeheartedly support his position that people themselves are largely responsible for ending up in hospital. I have often said that if people would lavish the same care and attention on their health as they do on their money and investments then the world's population would be a great deal healthier. Dr. Greenwood's letter eloquently presents the case for conventional medicine and one's personal responsiblity for health. It is reprinted in full in the "Letters to the Editor" section. Yours in health, Hans R. Larsen, Editor |
LETTERS TO THE EDITORAs always I enjoyed your most recent issue of International Health News. However, I do think you may have overstated your case somewhat by asserting there is a "massive" swing toward alternative medicine. As you know, I sit on both sides of the fence, and I just don't see it as you put it.
In my view the "massive swing" everyone talks about is a myth. There will always be a demand for crisis intervention, which is what the medical system is all about. Of course, those who choose to be pro-active with their health may be less prone to catastrophes, and that's as it should be, but it won't stop crises from occurring. A lot of people I see who say they are into "alternative medicine" are actually looking for a way to avoid the consequences of their own irresponsible living habits. In other words, the massive swing which you talk about - if it exists at all - may be driven by the "me generation's" narcissistic desire to avoid the pain of existence. If that is so then nothing really has changed. Michael Greenwood, MD, Canada
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ABSTRACTS
Prostate cancer risk and diet
MAASTRICHT, THE NETHERLANDS. Many studies have attempted to find an association between
prostate cancer risk and diet. Some studies have found an increased risk with high intakes of animal
products and calcium, others have been inconclusive. Researchers at Maastricht University have just
released the results of a major study regarding diet and prostate cancer risk. The study was part of the
Netherlands Cohort Study which involves 58,279 men aged 55 to 69 years when they enrolled in the
study in September 1986. The men completed a 150-item food frequency questionnaire at the beginning
of the study period and also provided detailed information relating to other potential risk factors for
cancer. After 6.3 years of follow-up 642 of the men had developed prostate cancer. The diet of these
men was compared to that of 1525 men without prostate cancer. The researchers concluded that the
overall consumption of fresh meat and poultry, fish, cheese, and eggs showed no correlation with
prostate cancer risk. Consumption of whole yoghurt was associated with a decreased risk, but no
correlation was found between calcium intake and prostate cancer risk. There was some indication that
certain cured meats (eg. sausages) were associated with an increased risk.
Ascorbic acid combats lead poisoning
SAN FRANCSICO, CALIFORNIA. Lead poisoning (elevated levels of lead in the blood) is a serious
problem in the United States. In 1984 it was estimated that 3-4 million children had lead levels exceeding
15 micrograms/dL (0.72 micromol/liter); significantly higher than the generally accepted safe level of 10
micrograms/dL. Although the elimination of lead additives in gasoline and paint and the phasing-out of
lead-soldered cans for foods and beverages have reduced the overall lead exposure, there are still large
reservoirs of lead in the soil and in old house paints. The problem is particularly acute in inner city cores
and tends to have a disproportionate impact among the poor. Chelation with calcium EDTA is standard
treatment for lead poisoning, but some studies have shown that oral chelation with ascorbic acid (vitamin
C) is equally effective. Now medical researchers at the University of California, San Francisco, report a
strong correlation between blood levels of ascorbic acid and lead. Their study involved 4,213 youths and
15,365 adults. A total of 0.5 per cent of the youths (aged 6 to 16 years) and 0.4 per cent of adults had
elevated lead levels. Among the youths, those with a serum ascorbic acid level of 30 micromol/L or less
were 89 per cent likely to have an elevated lead level than were the youths with an ascorbic acid level of
81 micromol/L or more. Among the adults, those with an ascorbic acid level of 15 micromol/L or less
were 65 per cent more likely to have an elevated lead level (greater than 20 microgram/L) than were the
adults with an ascorbic acid level of 70 micromol/L. The researchers cite several clinical trials in which
supplementation with ascorbic acid produced a marked decrease in blood lead levels and recommend
further large-scale trials to determine if vitamin C supplementation is an effective means of reducing lead
toxicity in exposed population groups. NOTE: This study was partially funded by Hoffmann-LaRoche Inc.,
a major manufacturer of pharmaceuticals and vitamins.
Nothing wrong with a healthy suntan
BRISTOL, UNITED KINGDOM. For years the medical establishment has been bombarding the public
with advice to stay out of the sun, slather on sunscreen, and in general consider the sun as an enemy
rather than as a friend. Fortunately, the public has been slow to accept this message and most people
still like to be in the sun and consider a suntan to be a sign of good health. The original reason for the
restricting sun exposure was to reduce the incidence of melanoma. Some studies had shown that a
severe sunburn, especially at a young age, and intermittent exposure to strong sunlight are indeed strong
risk factors for melanoma. Other studies, however, have shown that regular exposure to sunlight reduces
the risk of melanoma. Melanoma is a relatively rare disease. In 1995 fewer than 1400 people died from
this condition in England and Wales combined. In comparison, during the same period over 130,000 men
and women died from ischemic heart disease in the same geographic area. Researchers at the
University of Bristol are now sounding the warning bells. They point out that some sun exposure (without
sunscreen coverage) is required in order to produce enough vitamin D to prevent rickets, osteomalacia,
bone fractures, and perhaps multiple sclerosis. They also point to a recent study which found that
adequate vitamin D levels protect strongly against heart attacks. There is also considerable evidence
that sunlight exposure improves mood, may combat depression, and in general creates a subjective
feeling of greater wellbeing. The researchers conclude that the benefits of sunlight exposure may
outweigh the widely publicised adverse effects. Says one member of the research team "Those of us
who enjoy spending time in the sun can rest assured that the chance that we will be one of the people
dying from our tan is small."
Memory loss linked to vitamin E deficiency
INDIANAPOLIS, INDIANA. Oxidative stress is a major cause of accelerated aging and has been clearly
implicated in both Alzheimer's and Parkinson's disease. Antioxidants such as vitamin C and E and the
carotenoids have been shown to effectively combat oxidative stress. A team of researchers from Indiana
University now report that oxidative stress may also be involved in memory loss and that older people
with high vitamin E levels are less likely to suffer from memory loss than are people with low levels. Their
study involved 4809 older people (aged 60 years and over) and was part of the Third National Health and
Nutrition Examination Survey (NHANES III) carried out between 1988 and 1994. All participants were
given a test aimed at detecting memory loss (delayed word recall and delayed story recall) and also
provided blood samples for analysis of vitamins A, C and E, selenium, carotenoids, folate, calcium, iron,
and cholesterol. Overall, 7 per cent of the participants were found to have poor memory. Non-Hispanic
blacks had the highest prevalence of poor memory while non-Hispanic whites had the lowest. Higher
age, lower level of education, low family income (less than $20,000/year) and not enough to eat were all
associated with a higher incidence of memory loss. Blood serum levels of selenium, vitamins A and C,
and carotenoids (per unit of cholesterol) were not associated with poor memory. There was, however, a
clear correlation between vitamin E level (per unit of cholesterol) and memory loss. Participants with
vitamin E levels below 4.8 had a 175 per cent higher incidence of memory loss than did participants with
a level above 7.2. It is worth noting that high vitamin E levels were most prevalent among non-Hispanic
whites and among those taking vitamin supplements. Nevertheless, even after adjusting for all other
pertinent risk factors it was clear that people with a high vitamin E level were significantly less likely to
suffer from memory loss.
Parkinson's patients on l-dopa need folic acid
BOCHUM, GERMANY. People suffering from Parkinson's disease have an increased risk of heart
attacks and strokes. A team of German and Swiss medical researchers believe they have uncovered the
reason for this and propose a simple solution to the problem. The researchers studied a group of 48- to
73-year-old people. Fifteen of them had Parkinson's disease and were treated with levodopa plus
decarboxylase inhibitor (Sinemet), 15 had Parkinson's disease, but were not treated as yet, and 15 were
healthy controls. All study participants had their homocysteine levels measured after a 10-hour fast. The
drug-treated Parkinson's patients had an average level of 17.3 micromol/L as compared to 9.1 micromol/L
in the untreated group, and 9.2 micromol/L in the group of healthy controls. Other research has found
that men with a level of 15 micromol/L increase their risk of coronary heart disease by 60 per cent while
women increase it by 80 per cent. The risk of a stroke at the 15 micromol/L is two to five times higher
than at the 10 micromol/L level in both men and women and the risk of peripheral vascular disease (eg.
intermittent claudication) is seven times higher among people with elevated levels. The researchers
believe that prolonged treatment with levodopa and decarboxylase inhibitor increases the blood level of
homocysteine resulting in a greater risk for heart disease and stroke. They point out that elevated
homocysteine levels can be lowered easily and effectively by supplementation with folic acid (400-800
micrograms per day or more depending on homocysteine level). The research team concludes that
Parkinson's patients who are treated with levopoda should have their homocysteine levels monitored on a
regular basis and should supplement with folic acid as required. (Editor's Note: Folic acid is non-toxic and
no cases of overdosing have ever been reported. In these times of tight medical resources it would seem
reasonable to suggest that Parkinson's patients on levopoda routinely supplement with 400-800
micrograms per day - unless, of course, their physician has specific objections to this).
Is seeing drug salesmen a waste of time?
THORNTON HEATH, UNITED KINGDOM. Dr. David Griffith, a British consultant physician for care of
older people, makes an eloquent plea to try to convince physicians to spend less time seeing salesmen
from pharmaceutical companies and more time seeing their patients. Dr. Griffith points out that with
today's multitude of reliable information sources there is really little or no need to see drug
representatives in order to keep abreast of new developments. Not surprisingly, there is evidence that
the more reliant doctors are on salesmen-provided information the more irrational they are in their
prescription habits. Increased heath care costs are likely to be a further consequence of contact with
drug company representatives. The sale of selective serotonin reuptake inhibitors (Paxil, Prozac, etc.),
for example, have been far higher than would have been expected if their prescription was based on
scientific facts rather than on commercial hype. Says Dr. Griffith "There is potentially much to be gained
by changing our ways. We could cut costs, improve our prescribing practices - and save a little time in
our crowded schedules. With more new and expensive drugs now hitting the market, this might be an
ideal time for change."
New test accurately detects Helicobacter pylori infection
ANN ARBOR, MICHIGAN. A Helicobacter pylori infection is the main cause of stomach ulcers.
The presence of the infection can be positively established by endoscopy and analysis of tissue removed
from the stomach. The urea breath test is a rapid, non-invasive test which can also be used to detect the
infection, but it is somewhat less accurate than endoscopy. Performing the urea breath test is also time-
consuming and most general practitioners do not have the expertise and equipment required to do it
properly. Now a team of researchers from five American medical centers report the development of a
variant of the urea test which is quicker, less expensive, and can be performed by most doctors without
any special training. The new test involves the ingestion of urea labelled with a carbon radio isotope just
as does the present urea breath test. However, instead of measuring the presence of the isotope in the
breath after ingesting the urease the new test measures the presence of labelled carbon in bicarbonate in
the blood. All that is required is a standard sample of venous blood drawn 30 minutes after urease
ingestion. The new test is not only less invasive, cheaper, and easier to perform than previous tests, but
it is also very accurate with an accuracy of 93 per cent of that obtained by endoscopy and tissue analysis.
Note: This study was supported by Metabolic Solutions, Inc., a blood analysis laboratory.
Pipe smoking and lung cancer
LYON, FRANCE. It is a well established fact that the smoking of cigarettes increases the risk of lung
cancer by a factor of about 15. The situation regarding pipe and cigar smoking is not quite so clear and
some studies have shown comparatively little increase in lung cancer risk among cigar and pipe smokers.
Now a team of European researchers from nine major medical centers reports that pipe and cigar
smokers also face a vastly increased risk of lung cancer. Their study involved 5621 men with lung cancer
and 7255 matched controls. The researchers found that pipe smokers increased their risk of developing
lung cancer by a factor of 7.9 as compared to non-smokers while cigar and cigarillos (small cigars)
smokers increased their risk by a factor of 9. Cigarette smokers were found to have a 14.9 times higher
risk of lung cancer than were non-smokers. Cigar smokers who began their habit before the age of 20
years were particularly vulnerable to lung cancer as were those who smoked more than 15 grams per day
and had been smoking for a long time. Heavy smokers of cigars and cigarillos were found to have a 35
times greater risk than non-smokers and smokers who inhaled had a five times greater risk than smokers
who did not. The researchers conclude that cigar and pipe smoke is just as carcinogenic as cigarette
smoke and that previous results indicating that pipe and cigar smoking may be safer can be explained by
the fact that pipe and cigar smokers tend to smoke less and start the habit later in life.
Shark cartilage helps scleroderma victims
WAKEFIELD, RHODE ISLAND. Scleroderma (systemic sclerosis) is a serious disorder which is
characterized by a thickening and stiffening of the skin, blood vessels, and tissues in the lungs, heart, and
kidneys. The onset of the disease is usually between the ages of 30 and 50 years and women are
affected three times as often as men. The disease is painful and leads to a gradual loss of motion of the
joints. There is no effective cure. Now two physicians, Dr. Peter Himmel and Dr. Trina Seligman, report
that treatment with shark cartilage may help alleviate some symptoms of the disease. Their conclusion is
based on only four cases and clearly needs validation in larger trials. The four patients were all women
between the ages of 45 and 63 years who had suffered from scleroderma for 5 to 20 years when they
began the shark cartilage therapy. Each patient received 7 cc of shark cartilage extract (Car-T-Cell) daily
in the form of a vial which was ingested (sublingually) on an empty stomach. All patients experienced
improvements in their condition after a few months of therapy. One patient reported a significant
improvement in her pain and fibromyalgia, another increased her walking distance to a mile a day from
only a few blocks and was able to return to work, while a third reported a complete reversal of her arthritis
symptoms.
Rapid rise in the incidence of diabetes
SAN ANTONIO, TEXAS. It is estimated that over 13 million people in the United States suffer from
diabetes and that 650,000 new cases are diagnosed every year. Most diabetics (over 90 per cent) have
non-insulin-dependent diabetes mellitus (NIDDM) or type 2 diabetes. NIDDM usually starts in middle age
and is often associated with obesity. The disorder may lead to heart disease, kidney failure, and
blindness. Researchers at the Texas Health Science Center have just released the results of a major
study which shows that the number of new cases of type 2 diabetes diagnosed in a year has tripled
between 1987 and 1996. Their study involved 1995 Mexican Americans and 1231 non-Hispanic, white
Americans. The participants who were non-diabetic at baseline were enrolled in the study during the
period 1979 to 1988 and were followed for a seven- to eight-year period to determine the incidence of
new diabetes cases. During the follow-up a total of 225 Mexican Americans and 68 non-Hispanic whites
developed diabetes. Analysis of the collected data showed a clear trend toward a significant increase in
new diabetes cases. In Mexican Americans the seven- to eight-year incidence increased from 5.7 per
cent for participants enrolled in 1979 to 15.7 per cent for those enrolled in 1988. In non-Hispanic whites
the incidence rose from 2.6 per cent for participants enrolled in 1980 to 9.4 per cent for those enrolled in
1988. The significant increase in diabetes incidence held true even when adjusting for sex, age, ethnic
group, and neighbourhood (income and social level). Being older, living in a poorer neighbourhood, being
Mexican American, and being obese were all independently associated with an increased risk of
diabetes. The researchers also found a significant increase in the incidence of obesity (body mass index
greater than 27) over the study period. They conclude that the incidence of type 2 diabetes increased by
eight to ten per cent a year during the period 1987 to 1996 and warn that "obesity and diabetes could
easily become the preeminent US public health problem."
Epileptics may benefit from aromatherapy
BIRMINGHAM, UNITED KINGDOM. "There are simple ways of helping people with epilesy avoid
seizures, but unfortunately doctors and patients are generally not aware of them." So says Dr. Tim Betts,
a consultant neuropsychiatrist and senior lecturer at the University of Birmingham. Dr. Betts points out
that many epileptics know in advance when they are going to have a seizure and that about half know
what sets if off. He suggests that reducing stress levels through relaxation is an excellent idea for anyone
suffering from seizures. He is particularly impressed with the results using aromatherapy in combination
with massage. Aromatherapy massage using oils such as ylang ylang, bergamot, camomile, lavender,
and jasmine are profoundly relaxing and the feeling of relaxation they induce can, after a while, be
recaptured immediately by sniffing a small bottle of the oil. Dr. Betts has found that many epilepsy
patients after three or four aromatherapy massages are able to avoid seizures by gently inhaling lavender
or jasmine oil whenever they feel an impending seizure. In a small trial involving 50 epileptics he found
that a quarter of the patients eliminated their seizures altogether by using this method. Dr. Betts cautions
that rosemary and other oils containing camphor should not be used by epileptics. He also suggests that
patients should make an effort to become aware of what sets off their seizures and then avoid these
situations. Sitting too close to the set when watching television apparently is a fairly common
precipitating factor.
DHEA protects against prostate cancerWe do not usually report information based on animal experiments; however, the finding that DHEA can prevent or even reverse prostate cancer in laboratory rats seemed important enough to make an exception.
CHICAGO, ILLINOIS Prostate cancer is the second most common cause of cancer death in Western
male populations. It is estimated that about 18 per cent of American men will develop prostate cancer
during their lifetime. Some researchers believe that many more have the beginnings of prostate cancer,
but die from other causes before the cancer becomes invasive and fatal. Research has shown that the
hormone DHEA (dehydroepiandrosterone) inhibits the growth of both human and rat prostate cancer cells
in vitro (in test tubes). Now a team of researchers from the National Cancer Institute, the New
York University School of Medicine, and the ITT Research Institute reports that DHEA confers significant
protection against prostate cancer progression when given to laboratory rats as part of their diet. Their
experiment involved rats which were given carcinogenic chemicals to induce precancerous lesions in the
prostate. One group of rats had 1000 or 2000 mg of DHEA added to each kilogram of feed starting one
week before inducing the cancer. Other groups had 2000 mg of DHEA added per kilogram of diet one
week before induction, 20 weeks after induction or 40 weeks after induction. The rats received the DHEA
until the experiment was concluded 13 months after cancer induction. Control rats received no DHEA.
The researchers found a very significant decrease in the progression to full prostate cancer among the
rats given DHEA in their diets. This effect was evident whether the DHEA was given one week before or
20 or 40 weeks after cancer induction. They conclude that DHEA or a suitable derivative may be
effective in preventing the development and progression of prostate cancer in humans, but caution that
more work is required to ensure the DHEA's hormonal effects (conversion to testosterone and estrogenic
activity) are not detrimental.
Systolic blood pressure most important for older people
MILAN, ITALY. It is a well established fact that high blood pressure is a potent risk factor for heart
disease and subsequent death. In young and middle-aged people it is clear that systolic blood pressure
(SBP) of 140 mm or higher, a diastolic pressure (DBP) of 90 mm or higher or a combination of the two are
associated with increased risk. For older people (over 65 years of age) the situation is not quite so clear.
Some, but not all, previous studies have found that SBP is a stronger predictor of risk than is DBP. A
group of researchers involved with the SPAA (Studio sulla Pressione Arteriosa nell'Anziano) weigh in with
the results of a major study involving 3784 outpatients aged 65 years or older. The study participants had
repeated blood pressure measurements over a one-year period (both in the supine and sitting positions)
and were then followed up for 10 years to determine the association between blood pressure and
mortality. At baseline 79.9 per cent of the participants had a SBP of 140 mm or higher and 35.8 per cent
had a DBP of 90 mm or higher. At the end of the 10-year period 1561 of the participants had died. The
single-most important cause of death was cardiovascular disease which claimed 709 lives (45.4 per cent
of all deaths). Analysis of the blood pressure data showed a clear association between SBP and the risk
of dying from heart disease or other causes with people who have higher SBPs having the highest risk.
No correlation was found between DBP and mortality irrespective of whether baseline DBP was below or
considerably above 90 mm Hg. The researchers conclude that in the elderly a high SBP, but not a high
DBP, is associated with increased mortality especially from cardiovascular disease. They recommend
that this finding be taken into account when diagnosing and treating elderly people for high blood
pressure.
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NEWSBRIEFS
Avoid coffee before giving birth.
Antioxidants protect against Alzheimer's disease.
UV lights kill microbes in ventilation systems.
Mercury contaminated food linked to high blood pressure.
Cooked vegetables may be healthier.
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Victoria, BC, Canada V8S 1A5 Phone: (250) 384-2524 E-mail: health@pinc.com URL: http://vvv.com/healthnews/ ISSN 1203-1933.....Copyright © 1999 by Hans R. Larsen International Health News does not provide medical advice. Do not attempt self- diagnosis or self-medication based on our reports. Please consult your health-care provider if you wish to follow up on the information presented. |